Year: 2022
Type: conference-paper
Abstract: Catastrophic antiphospholipid syndrome (APS) is a severe acquired thrombophilia characterized by rapid development of thromboses in several organs, in presence of antiphospholipid antibodies. For histopathologic confirmation, thrombosis should be present without significant evidence of vessel wall inflammation. APS is a known association of systemic lupus erythematosus (SLE) and, when present with lupus, has the worst outcome. Peripheral vascular disease leading to digital gangrene is a well-recognized complication of APS, particularly in patients with SLE. Digital gangrene in SLE is a rare form of vascular injury and generally leads to digital amputation.
Authors: Amália Mapurunga Almeida, José Savio Menezes Parente, Carlos Nobre Rabelo Junior, Marco Felipe Castro da Silva, Míria Paula Vieira Cavalcante, Natalia Gomes Iannini, Francisco Afranio Pereira Neto, Liana Dourado Teixeira Figueiredo, Sofia Gomes Correia, Lucas Rodrigues Gomes, Marina Coelho Feitosa, Yury Pifano Varela
Language: English
Subfield: Rheumatology
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
OpenAlex ID: W4297797840