Work

Epstein-Barr Virus WZhet DNA Can Induce Lytic Replication in Epithelial Cells in vitro, although WZhet Is Not Detectable in Many Human Tissues in vivo

Year: 2020

Type: article

Abstract: WZhet is a rearranged and partially deleted form of the Epstein-Barr virus (EBV) genome in which the BamH1W region becomes juxtaposed with and activates BZLF1, resulting in constitutive viral replication. We tested whether WZhet induces viral replication in epithelial cells, and we studied its prevalence in a wide range of lesional tissues arising in vivo.

Source: Carolina Digital Repository (University of North Carolina at Chapel Hill)

DOI: 10.17615/qvf1-w038

Authors: Gulley, Margaret L., Elmore, Sandra H., Jones, Richard J., Ryan, Julie L., Schroeder, Jane C., Miller, George, Kenney, Shannon C.

Language: English

Topic: Viral-associated cancers and disorders

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Cancer Institute, Department of Pathology and Laboratory Medicine, University of North Carolina School of Medicine

OpenAlex ID: W4299704414

FWCI:

Cites:

Cited by: 1

Related to: 10