Three-Year Dentition Follow-up of a Paediatric Case with Malignant Infantile Osteopetrosis: A Review of the Literature
Year: 2022
Type: article
Study design: Case Report
Abstract: Malignant infantile osteopetrosis (MIO), the most severe form of osteopetrosis, also known as marble bone disease, has a high rate of infant mortality and causes severe medical and dental outcomes in children. The general oral findings of this disease are reduced vascularisation of the jawbone as a result of impaired osteoclastic activity, eruption disorders, embedded teeth, missing teeth, dental hypoplasia and misshaping, excessive luxations associated with undeveloped roots, increased incidence of decay, and periodontal membrane defects. The current case patient was diagnosed with MIO at 4 months of age and underwent bone marrow transplantation at the age 3 years. The dentition development of the male patient was followed by regular dental examinations from the years 7 through 10. The tooth development of a MIO paediatric patient is presented in this case report with a review of the literature.
Authors: Akleyin, Ebru, Polat, Yelda, Yavuz, Yasemin
Institutions: Dicle University, Harran University
Language: English
Subfield: General Dentistry
Field: Dentistry
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4306901409