Work

Role of adherent invasive Escherichia coli in pathogenesis of inflammatory bowel disease

Year: 2022

Type: review

Abstract: (AIEC) may contribute to a further understanding of IBD pathogenesis. This review explores the relationship between AIEC and the intestinal immune system, discusses the prevalence and relevance of AIEC in Crohn's disease and ulcerative colitis patients, and describes the relationship between AIEC and the disease site, activity, and postoperative recurrence. Finally, we highlight potential therapeutic strategies to attenuate AIEC colonization in the intestinal mucosa, including the use of phage therapy, antibiotics, and anti-adhesion molecules. These strategies may open up new avenues for the prevention and treatment of IBD in the future.

Source: World Journal of Clinical Cases

DOI: 10.12998/wjcc.v10.i32.11671

Authors: Lie Zheng, Sheng-Lei Duan, Yan-Cheng Dai, Shi-Cheng Wu

Institutions: Shaanxi Provincial Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine

Language: English

Topic: Inflammatory Bowel Disease

Subfield: Gastroenterology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4308016229

FWCI: 1.245

Cites: 138

Cited by: 43

Related to: 10