Year: 2022
Type: article
Study design: Case Report
Abstract: CD8+ encephalitis is a subacute encephalopathy associated with HIV infection. Pathophysiology is thought to be auto-reactive CD8+ cells attacking on HIV infected CD4+ cells and 'viral escape' phenomena (replication of CD8+ cells in CSF). We present a case of a 45-year-old man with well controlled HIV who developed CD8 encephalitis following Herpes simplex encephalitis. He had persistent encephalopathy for several weeks with status epilepticus and agitated delirium, and diagnosis remained elusive until a brain biopsy confirmed the diagnosis.
Source: Diagnostics
Authors: Rohan Sharma, Thomas Spradley, Morgan Campbell, Shubham Biyani, Pulkit Singhal, Hisham Elkhider, Krishna Nalleballe, Murat Gokden, Manoj Kumar, Nidhi Kapoor
Language: English
Topic: HIV Research and Treatment
Subfield: Virology
Field: Immunology and Microbiology
Domain: Life Sciences
Open Access status: gold
Estimated APC paid: $1,885
OpenAlex ID: W4308334219