Year: 2022
Type: article
Abstract: Ion microscopy allows for high-throughput mass spectrometry imaging. In order to resolve congested mass spectra, a high degree of timing precision is required from the microscope detector. In this paper we present an ion microscope mass spectrometer that uses a Timepix3 hybrid pixel readout with an optimal 1.56 ns resolution. A novel triggering technique is also employed to remove the need for an external time-to-digital converter (TDC) and allow the experiment to be performed using a low-cost and commercially available readout system. Results obtained from samples of rhodamine B demonstrate the application of multimass imaging sensors for microscope mass spectrometry imaging with high mass resolution.
Authors: Daniel Wood, Robert J. Burleigh, Natasha Smith, Daniela Bortoletto, Mark Brouard, Michael Burt, Andrei Nomerotski, Richard Plackett, Ian Shipsey
Institutions: University of Oxford, Brookhaven National Laboratory
Language: English
Subfield: Spectroscopy
Field: Chemistry
Domain: Physical Sciences
Open Access status: hybrid
Estimated APC paid: $5,000
OpenAlex ID: W4309246323