Increased Quality of Life in Patients with Breakthrough Cancer Pain after Individualized Therapy: the CAVIDIOM Study
Year: 2022
Type: article
Study design: Observational Study
Abstract: Aim: To evaluate the quality of life (QoL) in patients with breakthrough cancer pain (BTcP) in Spanish medical oncology departments. Patients & methods: In a prospective, observational, multicenter study, we assessed QoL using the EQ-5D-5L instrument at baseline and after 15 and 30 days of individualized BTcP therapy, as well as BTcP characteristics and treatment. Results: Patients (n = 118) were mainly women, over 64 years old and with advanced cancer. QoL improved at 15 (p = 0.013) and 30 days (p = 0.011) versus baseline. Individualized BTcP therapy consisted mostly of rapid-onset opioids (transmucosal fentanyl at doses of 67–800 μg) according to the physician evaluation. BTcP improved, including statistically significant reductions in intensity, duration, number of episodes in the last 24 h and time to onset of BTcP relief. Conclusion: QoL increased after individualized pain therapy in patients with advanced cancer and BTcP in medical oncology departments.
Source: Future Oncology
Authors: Paula González Villarroel, Josep Gumà Padró, Gloria Marquina, Noelia Martínez Jáñez, Emilio Esteban González, Antonio Antón, Miguel Berzosa Sánchez, Alberto Rodrigo Cáceres, Rafael López-López, Roberto Escala Cornejo, Pablo Borrega García, Raquel Marse Fabregat, Beatriz Castelo Fernández, Cristina López Bermudo, Carlos Camps
Institutions: Institut de Recerca Biomèdica Catalunya Sud, Hospital Universitari Sant Joan de Reus, Universidad Complutense de Madrid, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos, Hospital Universitario Ramón y Cajal, Hospital Universitario Central de Asturias, Hospital Universitario Miguel Servet, Instituto de Investigación Sanitaria Aragón, Hospital Universitari de Tortosa Verge de la Cinta, Hospital Universitari Arnau de Vilanova, Centro de Investigación Biomédica en Red de Cáncer, Complejo Hospitalario de Salamanca, Hospital San Pedro de Alcántara, Hospital Universitario Son Espases, Hospital Universitario La Paz, Universitat de València, Hospital General Universitario De Valencia
Language: English
Subfield: Anesthesiology and Pain Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
Funders: Angelini Pharma España, Angelini Pharma
OpenAlex ID: W4312019397