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Prevalence and Predictors of Osteoporosis in Patients of Interstitial Lung Disease: An Observational Study from North India

Year: 2022
Type: article
Study design: Observational Study
Abstract: IntroductIonInterstitial lung disease (ILDs) is a group of >200 diseases that is characterized by pulmonary fibrosis, often leading to progressive cough and breathlessness.Besides respiratory involvement, the disease is often associated with comorbidities such as coronary artery disease, [1] sleep-disordered breathing, [2] pulmonary hypertension, [3] gastro-esophageal reflux, [4] and depression, [5] that add to the symptoms and worsen the health-related quality of life of these patients.Osteoporosis is clinically important comorbidity reported in different chronic respiratory diseases such as chronic obstructive pulmonary disease (COPD), [6] cystic fibrosis, [7] and pulmonary hypertension.[8] Advanced age, lack of physical activity, poor nutritional status, tobacco smoking, long-term corticosteroid use, and systemic inflammation are some of the factors that increase the risk of osteoporosis in COPD patients.[6,9,10] As many of these factors are also common in ILD patients, these patients may be at high risk of developing osteoporosis.Studies done outside India have shown a 13%-44% prevalence of osteoporosis in ILD patients.Old age, low body mass index (BMI), and Hispanic ethnicity are some of the factors that might increase the risk of osteoporosis in ILD.[11,12] Recent studies have shown a significant burden of ILD among Indian patients.[13,14] However, studies evaluating bone mineral Prevalence and Predictors of Osteoporosis in Patients of Interstitial Lung Disease: An Observational Study from North India
Language: English
Field: Medicine
Open Access status: diamond
OpenAlex ID: W4313063949
FWCI: 0.319
Cites: 29
Cited by: 6
Related to: 10