Year: 2022
Type: article
Abstract: Diseases caused by Streptococcus pneumoniae are a serious medical and social problem for healthcare systems of all leading countries around the globe. In this regard, the relevance of their laboratory diagnostics increases, as the effectivenessof therapeutic, preventive, and anti-epidemic measures depends on it. Currently, there is no universal method of intraspecific identification of S.pneumoniae, which simultaneously possess high specificity, sensitivity, and reproducibility.For this purpose, new alternative strategies aimed at improving the quality of research are being developed. The reviewpresents data from domestic and foreign publications (electronic search databases eLibrary.Ru, ScienceDirect, Scopus,PubMed, Springerlink) on serotyping and genotyping of S.pneumoniae; the advantages and disadvantages of the methodsare analyzed. Epidemiologically significant serotypes and widespread clonal complexes of S.pneumoniae circulating onthe territory of the Russian Federation have been identified. The necessity of improving new methods of intraspecific typing of the pathogen is recognized.
Language: English
Subfield: Epidemiology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4313232144