Deterioration of Phosphate Homeostasis Is a Trigger for Cardiac Afterload ― Clinical Importance of Fibroblast Growth Factor 23 for Accelerated Aging ―
Year: 2022
Type: article
Abstract: Background: After the discovery of the Klotho gene, phosphate came into focus as a pathogenetic aging agent. Phosphate homeostasis is controlled by phosphate-regulating hormones: fibroblast growth factor 23 (FGF23), vitamin D3, and parathyroid hormone. This study investigated the relationship between the deterioration in phosphate homeostasis and arterial stiffness by measuring serum FGF23 concentrations.
Source: Circulation Reports
Institutions: Kumamoto University, Kumamoto Kinoh Hospital
Language: English
Subfield: Nephrology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4313489755