Work

Azapeptide activity-based probes for the SARS-CoV-2 main protease enable visualization of inhibition in infected cells

Year: 2023

Type: article

Abstract: The COVID-19 pandemic has revealed the vulnerability of the modern, global society.

Source: Chemical Science

DOI: 10.1039/d2sc04147b

Authors: Roeland Vanhoutte, Marta Barniol-Xicota, Winston Chiu, Laura Vangeel, Dirk Jochmans, Steven De Jonghe, Hadeer Zidane, Haim M. Barr, Nir London, Johan Neyts, Steven H. L. Verhelst

Institutions: KU Leuven, Rega Institute for Medical Research, Weizmann Institute of Science, Leibniz Institute for Analytical Sciences - ISAS

Language: English

Topic: SARS-CoV-2 and COVID-19 Research

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

Funders: Bundesministerium für Bildung und Forschung, Fonds Wetenschappelijk Onderzoek, KU Leuven, Onderzoeksraad, KU Leuven, Vlaamse regering, Herculesstichting, Ministerium für Kultur und Wissenschaft des Landes Nordrhein-Westfalen, Rega Foundation, Moonshot Research and Development Program

Awards: Profiling of protein depalmitoylation during adipogenesis using activity-based probes, G3637121363, G5033194471, G5069427589, G5446237700, G5970252578, Profiling of protein depalmitoylation during adipogenesis using activity-based probes, Combinatorial development of activity-based probes for various hydrolases, and their application in biomolecular profiling, G8900504558

OpenAlex ID: W4313646830

FWCI: 2.329

Cites: 33

Cited by: 12

Related to: 10