Work

Molecular Docking and the Pharmacokinetic Properties of the Anti-Viral Compounds Towards SARS-CoV- An In-silico Approach

Year: 2023

Type: article

Abstract: The main aim of this study is to determine the bioactive compounds which have drug-like properties and has the potential to combat the spike-glycoprotein of SARS-CoV-2. The 6LXT protein of covid-19 was chosen from the protein data bank as a target protein. The compounds which are potentially capable to bind with the target were picked from the PubChem database and docked using the tool Autodock 4.2. Molecular docking of the molecules was done with the best conformations of the ligands and grid s

Source: International Journal Of Pharmaceutical Research And Allied Sciences

DOI: 10.51847/z2mkwovoqc

Authors: Parthiban Brindha Devi, Yashi Asthana, Arumugam Sumitha, Ivo Romauld Sagayaraj

Institutions: Vels University, ACS Medical College and Hospital

Language: English

Topic: Computational Drug Discovery Methods

Subfield: Drug Discovery

Field: Pharmacology, Toxicology and Pharmaceutics

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: hybrid

OpenAlex ID: W4313706830