Work

Bolus of ropivacaine 0.1% versus 0.2% in obstetric epidural analgesia: a comparative prospective study

Year: 2023

Type: article

Abstract: Objective.Aim of this study is to compare the effect of the initial bolus: 10 ml of ropivacaine 0.2% (small volume, high concentration) and 20 ml of ropivacaine 0.1% (high volume, low concentration) during obstetric labour on the motor block, haemodynamic consequences, analgesia, and parturient satisfaction.Patients and Methods.56 parturients were included in this prospective, randomized, double-blind study.The parturients were randomized into two groups: group 1 receiving an initial bolus of 10 ml of ropivacaine at 0.2% + 5 gamma of sufentanil, and group 2 receiving an initial bolus of 20 ml of ropivacaine at 0.2% + 5 gamma of sufentanil.The main endpoint was the evaluation of motor block.The secondary judgment criteria were: haemodynamic consequences, evaluation of obstetric analgesia by visual analogical scale, evaluation of the sensory level and satisfaction of the parturient.Results.The haemodynamic consequences were comparable for the 2 groups (p > 0.05).The means of the VAS were similar (p > 0.05).Motor block was similar in the 2 groups (14.81% for group 1 versus 6.89% for group 2 with p = 0.57).A statistically significant difference was noted according to the sensory level which was higher in group 2 (p < 0.05).The mean satisfaction was without significant difference (p = 0.64).The adverse effects were similar in the two groups (p > 0.05).Conclusions.Our study does not show a benefit of the use of a high-volume low concentration compared to the use of small volume high concentration during the induction of the epidural.

Source: Italian Journal of Gynaecology and Obstetrics

DOI: 10.36129/jog.2023.95