A palmitate-rich metastatic niche enables metastasis growth via p65 acetylation resulting in pro-metastatic NF-κB signaling
Year: 2023
Type: article
Source: Nature Cancer
Authors: Patricia Altea-Manzano, Ginevra Doglioni, Yawen Liu, Alejandro M. Cuadros, Emma Nolan, Juan Fernández-García, Qi Wu, Mélanie Planque, Kathrin Julia Laue, Florencia Cidre-Aranaz, Xiao-Zheng Liu, Oskar Marin-Bejar, Joke Van Elsen, Ines Vermeire, Dorien Broekaert, Sofie Demeyer, Xander Spotbeen, Jakub Idkowiak, Aurélie Montagne, Margherita Demicco, H. Furkan Alkan, Nick Rabas, Carla Riera-Domingo, François Richard, Tatjana Geukens, Maxim De Schepper, Sophia Leduc, Sigrid Hatse, Yentl Lambrechts, Emily Jane Kay, Sergio Lilla, Alisa Alekseenko, Vincent Geldhof, Bram Boeckx, Celia de la Calle Arregui, Giuseppe Floris, Johannes V. Swinnen, Jean-Christophe Marine, Diether Lambrechts, Vicent Pelechano, Massimiliano Mazzone, Sara Zanivan, Jan Cools, Hans Wildiers, Véronique Baud, Thomas G. P. Grünewald, Uri Ben-David, Christine Desmedt, Ilaria Malanchi, Sarah-Maria Fendt
Institutions: VIB-KU Leuven Center for Cancer Biology, KU Leuven, Jiangsu University, Affiliated Hospital of Jiangsu University, The Francis Crick Institute, Tel Aviv University, German Cancer Research Center, Hopp Children's Cancer Center Heidelberg, Deutsches Konsortium für Translationale Krebsforschung, University of Pardubice, Université Paris Cité, NF-kappaB, Différenciation et Cancer, Cancer Research UK Scotland Institute, Science for Life Laboratory, Karolinska Institutet, University of Glasgow, Heidelberg University, University Hospital Heidelberg
Language: English
Subfield: Cancer Research
Domain: Life Sciences
Open Access status: green
Funders: Bayer, Gilead Sciences, Boehringer Ingelheim, Gilead Foundation, Wellcome Trust, Francis Crick Institute, Fondation Cancer, Cancer Research UK, Fonds Wetenschappelijk Onderzoek, KU Leuven, Karolinska Institutet, Vetenskapsrådet, Onderzoeksraad, KU Leuven, China Scholarship Council, Science for Life Laboratory, Fonds Baillet Latour, Fondation contre le Cancer, Université de Paris, Stand Up To Cancer, Medical Research Council, H2020 European Research Council
Awards: G1741973158, G1879733599, Exploiting a novel link between metabolism and acetylation to predict and to treat metastasis formation, G2387375797, Metabolic regulation of metastatic growth, G3282698938, Genomic dissection of cellular plasticity and transcriptional memory in drug tolerance., G5513433724, G5538931675, G5728391819, G5812294390, G5965680879, G6863181770, G7118244760, G7682345242, G814114247, G8556187869, G8726318895, G8843862321, G911949026
OpenAlex ID: W4318982589