Evaluation of Phytochemicals, Anti-inflammatory and Antioxidant Potential of Aegle marmelos L. Leaves
Year: 2023
Type: article
Abstract: Aegle marmelos is a deciduous tree with trifoliate leave commonly found in the Indian subcontinent. The present study is to diagnose the phytochemicals physiochemical, qualitative and quantitative estimation. Total phenolic content was recorded at 53.52±3.25 µg Gallic acid equivalent (GAE) /mg of plant extract, total tannin content was observed at 6.4±1.02 μg GAE/mg and total flavonoid content was recorded at 37.4±2.65 μg Quercetin equivalent/mg. The study also comprised the Anti-inflammatory and anti-oxidant activity of plant leaves. Anti-inflammatory activity was examined through the HRBC method and compared with the standard drug diclofenac sodium. Ethanolic extract of leaves shows significant anti-inflammatory activity and provides 61.04±2.89 % of protection against hemolysis at 2000µg/ml of leave extract whereas at the same concentration diclofenac sodium provides only 54.55±2.35 % protection against hemolysis. The antioxidant potential of plant extract examines through DPPH free radical scavenging method. Leave extract showed better antioxidant activity in comparison to ascorbic acid. IC50 of plant extract is 48.99 ±1.96 % which is also better than the value of IC50 of ascorbic acid which was recorded at 50.39±2.05. The study showed that leaves extract of the plant has significant potential for the treatment of oxidative stress and inflammation.
Authors: Abhishek Kumar Pandey, Preeti Pande
Institution: Kalinga University
Language: English
Subfield: Complementary and alternative medicine
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4319984101