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5P Physiologically relevant treatment models to investigate epigenetic mechanisms driving platinum resistance in ovarian high grade serous carcinoma

Year: 2023
Type: article
Abstract: The prognosis for patients with platinum-resistant ovarian High Grade Serous Carcinoma (HGSC) remains poor. BriTROC-1 data indicate that genomic alterations alone cannot explain acquired platinum resistance. We investigate epigenetic changes that may drive platinum resistance in HGSC.
Source: ESMO Open
DOI: 10.1016/j.esmoop.2023.100859
Authors: R. Ergasti, M.Q. Lim, G. Giannone, D. Ennis, I.C.A. Dye, H.B. Mirza, A. Fagotti, G. Scambia, I. McNeish
Language: English
Subfield: Oncology
Field: Medicine
Open Access status: gold
Estimated APC paid: $3,290
Funder: Eisai
OpenAlex ID: W4322012117
FWCI:
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