Work

Supplementary Methods from BRAF Fusions Define a Distinct Molecular Subset of Melanomas with Potential Sensitivity to MEK Inhibition

Year: 2023

Type: supplementary-materials

Abstract: PDF file - 104K, Supplementary Materials and Methods. Case histories of patients with BRAF fusions; FoundationOneTM and RNA sequencing assays and data analysis; cloning, transfections, drug treatment, and immunoblotting procedures; BRAF fusion detection and reverse phase protein array (RPPA) analysis from TCGA data.

DOI: 10.1158/1078-0432.22447278

Authors: Katherine E. Hutchinson, Doron Lipson, Philip J. Stephens, Geoff Otto, Brian D. Lehmann, Pamela L. Lyle, Cindy L. Vnencak-Jones, Jeffrey S. Ross, Jennifer A. Pietenpol, Jeffrey A. Sosman, Igor Puzanov, Vincent A. Miller, William Pao

Language: English

Topic: Melanoma and MAPK Pathways

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W4361881998

Cites: 10

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Related to: 10