Supplementary Figure 2 from α-Catulin Marks the Invasion Front of Squamous Cell Carcinoma and Is Important for Tumor Cell Metastasis
Year: 2023
Type: supplementary-materials
Abstract: PDF file - 44K, shRNA lentiviral system was used to generate stable MDA-MB-231 cell lines that were �-catulin-deficient. The specific knockdown of �-catulin in MDA-MB-231 cells (G85) compared to the non-silencing control (GNS) was confirmed by RT-PCR (A), real-time qPCR (A'), and western blot (B). In vitro cell migration (C) and invasion (D) was decreased in �-catulin-ablated MDA-MB-231 cells; cells were visualized with toluidine blue. Standard error bars are shown (n=4 for cell migration and n=4 for invasion assay). *** statistical significance was determined using t-test (p < 0.001) or * analysis of variant (ANOVA) (p <0.02)
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: gold
OpenAlex ID: W4362492494