Work

Benzo[b]naphtho[2,1-d]furans and 2-Phenylnaphthalenes from Streblus usambarensis

Year: 2023
Type: article
Abstract: High Resolution Image Download MS PowerPoint Slide Three new benzo[ b ]naphtho[2,1- d ]furans, usambarins A–C ( 1 – 3 ), five new 2-phenylnaphthalenes, usambarins D–H ( 4 – 8 ), a new flavan ( 9 ), and a new phenyl-1-benzoxepin ( 10 ) as well as two known compounds ( 11 and 12 ) were isolated from the extract of the stem and roots of Streblus usambarensis (Moraceae). The structures were deduced using NMR spectroscopic and mass spectrometric analyses, and those of compounds 1 and 4 were confirmed by X-ray crystallography. Usambarin D ( 4 ) demonstrated moderate antibacterial activity (MIC 9.0 μM) against Bacillus subtilis, while none of the tested compounds were effective against Escherichia coli .
Language: Hebrew
Subfield: Drug Discovery
Open Access status: hybrid
Estimated APC paid: $5,000
OpenAlex ID: W4365138331
FWCI:
Cites: 22
Cited by:
Related to: 10