Adherence to Adjuvant Endocrine Therapy and Its Determining Factors in Patients With Breast Cancer
Year: 2022
Type: conference-abstract
Abstract: Objective: This study aims to investigate the adherence rates to adjuvant hormone therapy in patients with early-stage breast cancer. Methods: Breast cancer patients with early invasive disease who are being treated with adjuvant hormone therapy for at least 6 months in a private oncology service were evaluated for adherence rates. Data collection was done using the RedCap software. The MMAS-8 scale was used to assess adherence to treatment, dividing patients into three groups as follows: low (<6 points), medium (6–8 points), or high adherence (8 points). Demographic and clinical characteristics were assessed for the three adherence groups. Results: From June to December 2021, a total of 60 patients were recruited. The median age was 60.3 years, and 23.3% were premenopause. About demographic statistics, 80% have a college degree, 35% live alone, and 30% have comorbidities. About breast cancer, 50% were in stage I, 50% received chemotherapy, 10% received HER2 blockade, and 26 patients (43.3%) used letrozole. Analyzing adherence, 45% had low/medium adhesion and 55% had high adhesion. There was no association between adherence rates and demographics, clinical and pathological characteristics, except for ECOG Performance Status (PS). All patients with PS ECOG 1 had low/medium adherence (p=0.036). More patients who live alone had low or medium adherence, whereas more patients who live together had high adherence. There was no difference in the type of hormonal treatment and adherence. Conclusion: Preliminary results show high adherence in only 55% of patients, lower than reported in previous studies. This result draws attention because it can compromise survival. We will continue the recruitment of patients in the private service and start in the public service to assess the rate of adherence in a larger population and the relationship with demographic characteristics.
Source: Mastology
Institutions: University Center of Brasília, Hospital Sírio-Libanês
Language: English
Subfield: Family Practice
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
OpenAlex ID: W4366705266