Visible light-induced metal-free synthesis of quinoxalines using Rose Bengal as a photocatalyst
Year: 2023
Type: article
Abstract: An efficient eco-friendly photocatalytic method was developed for the synthesis of pharmaceutically highly sought-after quinoxalines.This route is a simple condensation between o-phenylenediamine and an α-hydroxy ketone in methanol at room temperature in the presence of the organic dye Rose Bengal (4,5,6,7-tetrachloro-2',4',5',7'-tetraiodofluorescein) as a photocatalyst.Using this protocol, a library of examples with various ophenylenediamines and α-hydroxy ketones was prepared.This is a practically useful method for the development of quinoxaline derivatives of biological importance in good to excellent yields.
Source: ARKIVOC
Institution: Vardhaman College of Engineering
Language: English
Subfield: Organic Chemistry
Field: Chemistry
Domain: Physical Sciences
Open Access status: diamond
OpenAlex ID: W4367307664
