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An Efficient, One-Pot Synthesis of 1,3-Disubstituted imidazo[1,5-a]pyridines, Fe(OTf)3 Mediated C-C Bond Formation

Year: 2023

Type: article

Abstract: A vital approach of Fe(OTf)3 and MS3Å (molecular sieves 3Å) mediated one pot synthesis of 1,3-disubstituted imidazo[1,5-a]pyridines from dithioester, 2-methylaminopyridine and alcohol. This methodology involves the intramolecular cyclization and C–C bond formation under mild condition and operates in a single step yielding the products in good to excellent yields. This protocol was compatible to construct various 1,3-disubstituted imidazo[1,5-a] pyridines derivatives.

Source: Asian Journal of Chemistry

DOI: 10.14233/ajchem.2023.27602

Authors: T.C. Raveesha, Kemparajegowda, Hassan A. Swarup, B.K. Kempegowda, T. Demappa

Institution: Karnataka State Open University

Language: English

Topic: Synthesis of heterocyclic compounds

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: diamond

OpenAlex ID: W4367334243

FWCI:

Cites: 26

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Related to: 10