A Case of CMV Infection Presenting as Low Grade Fever in a Patient with Chronic Kidney Disease on Maintenance Haemodialysis
Year: 2022
Type: article
Study design: Case Report
Abstract: Cytomegalovirus belongs to Herpes Virus Family Herpesviridae, or human herpesvirus-5 (HHV-5). Manifests as asymptomatic to severe end-organ dysfunction in immunocompromised patients. It remains dormant after intial infection, reactivation occurs in immunosuppressed individualswhere it is more aggressive, causing hepatitis which may lead to fulminant liver failure, retinitis characterized by a "pizza pie appearance" on ophthalmic exam, esophagitis, colitis, pneumonitis, polyradiculopathy, transverse myelitis or encephalitis.An elderly male with chronic kidney disease on haemodialysis presented with non resolving fever and cough of duration more than 2 weeks.He was on multiple antibiotic regime and had blood investigations done.CT Thorax followed by BAL for CMV PCR lead to the diagnosis.Histopathological identification of CMV inclusion bodies is the gold standard for diagnosis.But, Quantitative PCR assays are the preferred method for viral detection.
Authors: Anirban Ray, Sushmita Roy Chowdhury, S. Unnithan, Angshuman Mukherjee, Pradip Mondal
Institution: Fortis Hospital
Language: English
Subfield: Epidemiology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4367336689