Work

Mishandling of immortal time bias in observational studies- we can do better

Year: 2022

Type: article

Abstract: initiation of treatment; otherwise, the patient will be assigned to the untreated group.Immortal time bias is introduced when this period of "immortality" is either mishandled or ignored in the assessment of treatment effect.This bias has been adequately described in the literature and some solutions have also been offered.However, it still remains more common practice in observational studies involving treated versus untreated patients, to acknowledge it as a limitation only and not directly address it adequately in the analysis.[1][2][3][4][5][6][7]

Source: Biometrics & Biostatistics International Journal

DOI: 10.15406/bbij.2022.11.00366

Author: Victor A Kiri

Institution: LabCorp (United States)

Language: English

Topic: Advanced Causal Inference Techniques

Subfield: Statistics and Probability

Field: Mathematics

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4367460083