Work

Generation of Human Embryonic Stem Cell-Derived Lung Organoids for Modeling Infection and Replication Differences between Human Adenovirus Types 3 and 55 and Evaluating Potential Antiviral Drugs

Year: 2023

Type: article

Abstract: Human adenovirus (HAdV) infections are a major threat worldwide. HAdV-3 is one of the most predominant respiratory pathogen types found in children.

Source: Journal of Virology

DOI: 10.1128/jvi.00209-23

Authors: Shanshan Zhao, Xiaowei Wu, Zhihong Tan, Yi Ren, Lian Li, Junxian Ou, Ying Lin, Hongbin Song, Liqiang Feng, Donald Seto, Jianguo Wu, Qiwei Zhang, Zhili Rong

Institutions: Southern Medical University, Jinan University, Chinese Academy of Sciences, Guangzhou Institutes of Biomedicine and Health, State Key Laboratory of Respiratory Disease, George Mason University

Language: English

Topic: Virus-based gene therapy research

Subfield: Genetics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: bronze

Funders: National Natural Science Foundation of China, Guangdong Science and Technology Department, National Key Research and Development Program of China, Fundamental Research Funds for the Central Universities, Basic and Applied Basic Research Foundation of Guangdong Province

Awards: 潜在主转录因子Cebpa调节II型肺泡细胞的发育、稳态及再生的分子机制研究, G1419713913, G1430642322, G3072428880, G3304656609, G3348307466, G3523954668, G376603064, G3948786894, G4638162253, G5956465385, G6839237722, G6857372607, G7842849146, G8096150218, G8695446210

OpenAlex ID: W4367550232

FWCI: 4.451

Cites: 66

Cited by: 28

Related to: 10