Work

Discovery of a Potent and Oral Available Complex I OXPHOS Inhibitor That Abrogates Tumor Growth and Circumvents MEKi Resistance

Year: 2023

Type: article

Source: Journal of Medicinal Chemistry

DOI: 10.1021/acs.jmedchem.2c01844

Authors: Peng He, Juanjuan Feng, Xinting Xia, Yue Sun, Jia He, Tian Guan, Yangrui Peng, Xueli Zhang, Mingyao Liu, Xiufeng Pang, Yihua Chen

Institutions: East China Normal University, Southern Medical University

Language: English

Topic: Cancer, Hypoxia, and Metabolism

Subfield: Cancer Research

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

Funders: Innovative Research Team of High-level Local University in Shanghai, National Natural Science Foundation of China, Science and Technology Commission of Shanghai Municipality, East China Normal University

Awards: G1101989689, G2773571048, G4279738476, G8469177929, G851126022

OpenAlex ID: W4367673307

FWCI: 2.827

Cites: 48

Cited by: 31

Related to: 10