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A case study of left visual neglect after right pontine lesion: pathophysiological evidence for the infratentorial involvement in human visual attention

Year: 2023

Type: article

Abstract: Visuospatial attention and its most common disturbance, hemispatial neglect, are typically associated with extended cortical networks. However, recent accounts challenge this corticocentric view and advocate the role of infratentorial structures. We describe, for the first time in a human, the occurrence of contralesional visual hemispatial neglect after a focal lesion in the right pons. We provide causal, lesion-based evidence for a pathophysiological mechanism involving the disconnection of cortico-ponto-cerebellar and/or tecto-cerebellar-tectal pathways passing through the pons.

Source: Journal of Neurophysiology

DOI: 10.1152/jn.00123.2023

Authors: Dario Cazzoli, Brigitte C. Kaufmann, Henrik Rühe, Nora Geiser, Tim Vanbellingen, Thomas Nyffeler