Year: 2023
Type: review
Abstract: Metabolic syndrome X has been known to be a risk factor for the development of cardiovascular dysfunction. Insulin resistance, diabetes mellitus and serum lipid abnormalities, which are all seen in metabolic syndrome X, have been found to negatively impact heart function, leading to heart failure in particular. Heart failure is a condition resulting when the heart is unable to perform its function of providing sufficient blood flow to meet the body's requirements. The treatment of heart failure in metabolic syndrome X varies based on the various components of metabolic syndrome X, which include obesity, hyperglycemia, hypertension and dyslipidemia. Obesity is regarded as one of the derangements seen in patients with metabolic syndrome X. It is a significant risk factor in the development of cardiovascular disease, which may eventually lead to heart failure. However, the obesity paradox suggests that obesity provides a higher chance of survival in patients with metabolic syndrome and heart failure. This review article focuses on the pathophysiology of heart failure in patients who already have metabolic syndrome X, as well as the therapeutic management complexity of the two conditions taking into consideration the protective role provided by obesity.
Source: Discoveries
DOI: 10.15190/d.2023.1
Institutions: University of Ilorin, University of Khartoum, Sir Sayajirao General Hospital Medical College, Tbilisi State Medical University, Lokmanya Tilak Municipal General Hospital and Lokmanya Tilak Municipal Medical College, Ross University School of Medicine, University of Perpetual Help System DALTA, Grant Medical College and Sir Jamshedjee Jeejeebhoy Group of Hospitals
Language: English
Subfield: Cardiology and Cardiovascular Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4378071990