Work

Molecular Characterization and Sterol Profiles Identify Nonsynonymous Mutations in ERG2 as a Major Mechanism Conferring Reduced Susceptibility to Amphotericin B in Candida kefyr

Year: 2023

Type: article

Abstract: Some yeast species exhibit intrinsic resistance or rapidly acquire resistance to azole antifungals. Despite >50 years of clinical use, resistance to amphotericin B (AMB) among yeast species has been extremely rarely reported until recently.

Source: Microbiology Spectrum

DOI: 10.1128/spectrum.01474-23

Authors: Mohammad Asadzadeh, Wadha Alfouzan, Josie E. Parker, Jacques F. Meis, Steven L. Kelly, Leena Joseph, Suhail Ahmad

Institutions: Kuwait University, Cardiff University, University of Cologne, Radboud University Medical Center, Canisius-Wilhelmina Ziekenhuis, University Hospital Cologne, Swansea University

Language: English

Topic: Antifungal resistance and susceptibility

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,500

Funder: Kuwait University

OpenAlex ID: W4382010542

FWCI: 3.082

Cites: 62

Cited by: 16

Related to: 10