Work

Risk of multi-drug-resistant organism acquisition from prior bed occupants in the intensive care unit: a meta-analysis

Year: 2023

Type: review

Study designs: Systematic Review, Meta-Analysis

Abstract: method and Q test. Eight articles were analysed using a random-effects model. Of the 8147 patients exposed to prior bed occupants infected or colonized with MDROs, 421 had acquired MDROs. The control group consisted of 55,933 patients without exposure factors, of which 1768 had been infected/colonized with MDROs. The pooled acquisition OR for MDROs was 1.80 (95% CI: 1.42, 2.29), P<0.00001. Subgroup analysis based on multi-drug-resistant Gram-positive and Gram-negative organisms was conducted using a fixed-effects model. The results significantly varied between the groups. Heterogeneity was partially explained by the MDRO type. In conclusion, exposure of bed occupants to infected/colonized MDROs significantly increased the risk of MDRO acquisition in subsequent bed occupants.

Source: Journal of Hospital Infection

DOI: 10.1016/j.jhin.2023.06.020

Authors: G.Y. Gu, M. Chen, J.C. Pan, X.L. Xiong

Institution: Nanjing Medical University

Language: English

Topic: Infection Control in Healthcare

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $3,540