Work

Prolonged Fever and Severe Hypercalcemia Revealing Systemic Extrapulmonary Sarcoidosis: A Lesson to be Learned

Year: 2023

Type: article

Abstract: Sarcoidosis often manifests with pulmonary involvement, making isolated extrapulmonary presentations rare and diagnostically challenging. We present the case of a 43-year-old woman who presented with prolonged fever, deep lymphadenopathy, massive splenomegaly, hepatomegaly, and severe hypercalcemia, mimicking malignancy. The diagnosis of sarcoidosis was established after the failure of anti-tubercular therapy, exclusion of differential diagnosis, and the subsequent development of cutaneous sarcoids. This case highlights the importance of recognizing isolated extrapulmonary pseudo-tumoral presentations of sarcoidosis, which can lead to delayed diagnosis.

Source: Oman Medical Journal

DOI: 10.5001/omj.2025.10

Authors: Ines Kechaou, Rym Abida, Hamdi Mohamed Salah, Eya Cherif, Lamia Ben Hassine

Institutions: Hôpital Charles-Nicolle, Tunis El Manar University

Language: English

Topic: Sarcoidosis and Beryllium Toxicity Research

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4383099345

FWCI: 0.173

Cites: 1

Cited by: 1

Related to: 10