Year: 2022
Type: article
Study design: Observational Study
Abstract: Catha edulis Forsk leaves " Khat " are chewed daily by a high proportion of the adult population in Yemen .The present study investigated the relationship between blood coagulation and khat chewing .In our study , we investigated the blood coagulation tests in two groups namely khat chewers group (n:30) and non– khat chewers group (n:60). The blood coagulation tests included bleeding time , clotting time , prothrombin time , partial thromboplastin time and platelets count. Statistical testing for data analysis included the student's t-test and chi 2 test. The results presented show the level of bleeding time , clotting time , prothrombin time , platelets count and platelets aggregation to be significantly different between khat chewers and non – khat chewers (p< 0.05) , we observed decrease in bleeding time , clotting time and prothrombin time in khat chewers less than normal values and we also observed enhance in platelets aggregation in khat chewers in comparison with non – khat chewers . The results presented show the level of partial thromboplastin time to be non -significantly different (p > 0.05) between both groups . The study concluded the khat chewing effects on blood coagulation physiology and consider as risk factor for blood coagulation system.
Language: English
Subfield: Hematology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4383428591