Work

Design, synthesis and biological evaluation of indazole derivatives as selective covalent inhibitors of FGFR4 in wild-type and gatekeeper mutants

Year: 2023

Type: article

Source: European Journal of Medicinal Chemistry

DOI: 10.1016/j.ejmech.2023.115628

Authors: Yingyue Yang, Xiaojie He, Zulong Li, Kai Ran, Ningyu Wang, Lifeng Zhao, Zhihao Liu, Jun Zeng, Bo Chang, Qiang Feng, Qiangsheng Zhang, Luoting Yu

Institutions: Sichuan University, West China Hospital of Sichuan University, State Key Laboratory of Biotherapy, Chongqing University of Arts and Sciences, Southwest Jiaotong University, Chengdu University, Chengdu Normal University

Language: English

Topic: Heterocyclic Compound Synthesis and Bioactivity

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: closed

OpenAlex ID: W4383533958

FWCI: 1.265

Cites: 27

Cited by: 13

Related to: 10