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Discovery of IACS-52825, a Potent and Selective DLK Inhibitor for Treatment of Chemotherapy-Induced Peripheral Neuropathy

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Year: 2023
Type: article
Source: Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.3c00788
Authors: Kang Le, Michael J. Soth, Jason B. Cross, Gang Liu, William J. Ray, Jiacheng Ma, Sunil G. Goodwani, Paul J. Acton, Virginie Buggia-Prevot, Onno Akkermans, John Barker, Michael L. Conner, Yongying Jiang, Zhen Liu, Paul McEwan, Jennifer Warner-Schmidt, Alan Xu, Matthias Zebisch, Cobi J. Heijnen, Brett Abrahams, Philip Jones
Institutions: The University of Texas MD Anderson Cancer Center, Evotec (United Kingdom), Rice University
Language: English

Topic: Cancer Treatment and Pharmacology
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
SDG: Good health and well-being

Open Access status: closed

Funders: Cancer Prevention and Research Institute of Texas, University of Texas MD Anderson Cancer Center
OpenAlex ID: W4384028600
FWCI: 2.912
Cites: 22
Cited by: 23
Related to: 10
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