Work

Pyruvate kinase deficiency mutant gene carriage in stray cats and rescued cats from animal hoarding in Hokkaido, Japan

Year: 2023

Type: article

Abstract: The mutant allele frequency of the Pyruvate kinase (PK) gene has been investigated mostly in pure breed cats. We investigated the PK mutant gene in stray and animal hoarding mongrel cats in Hokkaido, Japan. We also investigated the kinship of individuals carrying the mutant gene. Genotyping was conducted using the previously reported real-time PCR method. Fourteen microsatellite markers were used to identify the parents and offspring of cats carrying the PK mutant gene, and some kinship such as parent-offspring and siblings was observed. Some stray and animal hoarding cats carried the PK mutation gene and that consanguinity was confirmed among these cats indicated that the PK mutation gene was spread by unregulated interbreeding.

Source: Journal of Veterinary Medical Science

DOI: 10.1292/jvms.23-0091

Authors: Hiroshi UENO, Tomohito ITOH, Toyohiko NASUNO, Wataru KONNO, Atsushi KONDO, Ikuo KONISHI, Hisao INUKAI, Daiki KOKUBO, Mitsuhiro ISAKA, Md Shafiqul ISLAM, Osamu YAMATO

Institutions: Kyoto University, Institute for the Evolutionary Origins of Human Behavior, Kyoto University, Rakuno Gakuen University, Kagoshima University

Language: English

Topic: Genetic and phenotypic traits in livestock

Subfield: Genetics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: diamond

OpenAlex ID: W4385267263

FWCI: 0.243

Cites: 11

Cited by: 2

Related to: 10