Year: 2023
Type: article
Study design: Observational Study
Abstract: There is a lack of consensus of the frequency of follow-up of laboratory parameters during isotretinoin treatment. We conducted a retrospective analysis of the changes in laboratory parameters used in daily practice for patients with acne who were treated with isotretinoin to determine the optimum test repetition frequency. Patient demographic data; cumulative isotretinoin doses; alanin transaminase (ALT), aspartate transaminase (AST), γ-glutamyltransferase (GGT), creatinine kinase (CK), low-density lipoprotein cholesterol (LDL-C), and triglyceride (TG) levels during treatment were recorded. Our findings support the idea that routine monthly monitoring of normal laboratory parameters is unnecessary and wasteful. Periodic monitoring of abnormal laboratory parameters should be considered on an individual basis.
Source: Cutis
DOI: 10.12788/cutis.0808
Authors: Metin Özaslan, Dilek Peker
Institution: Konya Numune Hastanesi
Language: English
Subfield: Dermatology
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
OpenAlex ID: W4385694641