Work

Thermal Injury Protocol to Study Healing, With and Without Infection, in Guinea Pig (Cavia porcellus) Model

Year: 2023

Type: article

Abstract: Experimental healing studies in humans are complex and difficult to replicate in vitro.Hence, animal models are needed to study the different stages involved.The guinea pig (Cavia porcellus) is a model close to human physiology, including the lack of vitamin C synthesis, a precursor of collagen fibers for healing.The thermal injury in this animal makes it possible to study all the stages of healing, taking few days to show tissue repair in the processes with and without localized infection.The aim of this work was to systematize an experimental guinea pig (Cavia porcellus) animal model protocol for studies on healing with and without localized infection.

Source: International Journal of Morphology

DOI: 10.4067/s0717-95022023000401053

Authors: Jessica Salvo, Carolina Schencke, Mónica Pávez, Carlos Veuthey, Mariano del Sol

Institutions: Universidad de La Frontera, Universidad Santo Tomás, Universidad Autónoma de Chile

Language: English

Topic: Wound Healing and Treatments

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4385804281