Work

New Opportunities of Electrochemistry for Monitoring, Modulating, and Mimicking the Brain Signals

Year: 2023

Type: article

Abstract: High Resolution Image Download MS PowerPoint Slide In vivo electrochemistry is a powerful key for unlocking the chemical consequences in neural networks of the brain. The past half-century has witnessed the technology revolutionization in this field along with innovations in electrochemical concepts, principles, methods, and devices. Present applications of electrochemical approaches have extended from measuring neurochemical concentrations to modulating and mimicking brain signals. In this Perspective, newly reported strategies for tackling long-standing challenges of in vivo electrochemical brain monitoring (i.e., basal level measurement, electroactivity dependence, in vivo stability, neuron compatibility, multiplexity, and implantable device fabrication) are highlighted. Moreover, recent progress on neuromodulation tools and neuromorphic devices in electrochemical frameworks is introduced. A glimpse of future opportunities for electrochemistry in brain research is offered at last.

Source: JACS Au

DOI: 10.1021/jacsau.3c00220

Authors: Fei Wu, Ping Yu, Lanqun Mao

Institutions: Beijing Normal University, Chinese Academy of Sciences, Beijing National Laboratory for Molecular Sciences, Institute of Chemistry

Language: English

Topic: Neuroscience and Neural Engineering

Subfield: Cellular and Molecular Neuroscience

Field: Neuroscience

Domain: Life Sciences

Open Access status: gold

Estimated APC paid: $5,000

Funders: National Natural Science Foundation of China, National Key Research and Development Program of China