Retrospective Evaluation of Child Cases Followed with the Prediagnosis of Crimean-Congo Hemorrhagic Fever
Year: 2023
Type: article
Study design: Observational Study
Abstract: Aim: The aim of our study is to evaluate the clinical, demographic and laboratory findings of the patients who were followed up with the diagnosis of Crimean-Congo hemorrhagic fever (CCHF) in Gaziosmanpaşa University Medical Faculty Child Health and Diseases Service. This study was carried out with the aim of this study was to observe the importance of early diagnosis, observing the effects of the supportive treatment, documenting hospitalization time and the complications during the treatment. Material and Method: The study was carried out in a single center, Gaziosmanpaşa University Faculty of Medicine, Pediatrics Service in accordance with the Declaration of Helsinki Principles. Medical records of patients who were followed up with a prediagnosis of CCHF between January 2012 and July 2016 were retrospectively reviewed. Epidemiological, demographic and clinical characteristics, laboratory data, treatment methods and results of all cases were evaluated from patient files. Results: Between January 2012 and July 2016, a total of 100 patients with CCHF were detected. 52 % of the patients came from rural areas. The most applications were in April and June ( 69 % ) months. 100 % of the patients had a history of contact with ticks. The main symptoms and signs were fever (38%), haematological findings (34%), malaise ( 47 % ), abdominal pain (11 %), headache (25 %) and muscle pain (44 %). At the time of admission to the hospital, 6 % of patients had thrombocytopenia, 26 % had leukopenia, 26 % had elevated aspartate aminotransferase (AST), 12 % had elevated alanine aminotransferase (ALT), 44 % had elevated lactate dehydrogenase (LDH), 70 % had elevated creatine phosphokinase (CPK), 8 % had prolonged prothrombin time (PT), prolonged active partial thromboplastin time (aPTT) in 28 % and elevated international normalised ratio (INR) in 13 %. All patients underwent liquid-electrolyte therapy for support, 5 % aphasic platelet suspension, 13 % fresh frozen plasma, 12 % repeated erythrocyte suspension, and 13 % received ribavirin treatment. All of the patients who were included in the study were discharged with recovery. Conclusion: In conclusion, clinical manifestations of CCHF are similar to adults in children and CCHF is more favorable in children. There is no definitive proven treatment method yet, and most of the treatment is supportive treatment.
Authors: Ünüvar Gök, Şeyma, Karaaslan, Erhan, Çamcı, Melih, Gök, Alper, Demirel, Bulut
Language: English
Topic: Viral Infections and Vectors
Subfield: Infectious Diseases
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W4385963873