Head-to-Head Comparison of FDG and Radiolabeled FAPI PET: A Systematic Review of the Literature
Year: 2023
Type: review
Study design: Systematic Review
Abstract: FAPI-based radiopharmaceuticals are a novel class of tracers, mainly used for PET imaging, which have demonstrated several advantages over [18F]FDG, especially in the case of low-grade or well-differentiated tumors. We conducted this systematic review to evaluate all the studies where a head-to-head comparison had been performed to explore the potential utility of FAPI tracers in clinical practice. FAPI-based radiopharmaceuticals have shown promising results globally, in particular in detecting peritoneal carcinomatosis, but studies with wider populations are needed to better understand all the advantages of these new radiopharmaceuticals.
Source: Life
DOI: 10.3390/life13091821
Authors: Priscilla Guglielmo, Pierpaolo Alongi, Lucia Baratto, Elisabetta Abenavoli, Ambra Buschiazzo, Greta Celesti, Miriam Conte, Rossella Filice, Joana Gorica, Lorenzo Jonghi-Lavarini, Helena Lanzafame, Riccardo Laudicella, Maria Librando, Flavia Linguanti, Francesco Mattana, Alberto Miceli, Laura Olivari, Leandra Piscopo, Cinzia Romagnolo, Giulia Santo, Antonio Vento, Fabio Volpe, Laura Evangelista
Institutions: Istituto Oncologico Veneto, Lucile Packard Children's Hospital, Stanford Medicine, Stanford University, Azienda Ospedaliero-Universitaria Careggi, Azienda Sanitaria Ospedaliera S.Croce e Carle Cuneo, University of Messina, Sapienza University of Rome, University of Palermo, Essen University Hospital, University of Florence, European Institute of Oncology, Azienda Ospedaliera Nazionale SS. Antonio e Biagio e Cesare Arrigo, Ospedale Sacro Cuore Don Calabria, University of Naples Federico II, Azienda Ospedaliero-Universitaria delle Marche, Magna Graecia University, Humanitas University, IRCCS Humanitas Research Hospital
Language: English
Subfield: Biochemistry
Domain: Life Sciences
Open Access status: gold
Estimated APC paid: $2,002
OpenAlex ID: W4386255779