Work

Interrogating bioinspired ESIPT/PCET-based Ir( iii )-complexes as organelle-targeted phototherapeutics: a redox-catalysis under hypoxia to evoke synergistic ferroptosis/apoptosis

Year: 2023

Type: article

Abstract: We investigated organelle-targeted bioinspired ESIPT/PCET-based Ir(iii)-complexes as promising (photo)chemotherapeutic lead compounds which actively operational in redox-catalysis under hypoxia to evoke synergistic ferroptosis/apoptosis.

Source: Chemical Science

DOI: 10.1039/d3sc03096b

Authors: Maniklal Shee, Dan Zhang, Moumita Banerjee, Samrat Roy, Bipul Pal, Anakuthil Anoop, Youyong Yuan, N. D. Pradeep Singh

Institutions: Indian Institute of Technology Kharagpur, South China University of Technology, Indian Institute of Science Education and Research Kolkata

Language: English

Topic: Metal complexes synthesis and properties

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

Funders: Department of Science and Technology, Ministry of Science and Technology, India, University Grants Commission, South China University of Technology, Science and Engineering Research Board, National Key Research and Development Program of China

Awards: G1968881378, G4461152690, G7086398634, G7892608281

OpenAlex ID: W4386263296

FWCI: 2.601

Cites: 80

Cited by: 21

Related to: 10