Efficacy and safety of SPN-812 (extended-release viloxazine) in children and adolescents with attention-deficit/hyperactivity disorder: a systematic review and meta-analysis
Year: 2023
Type: study-registration
Study design: Systematic Review
Abstract: eview question / Objective P:children and adolescents with ADHD; I:SPN-812; C:placebo; O:ADHD-RS-5, Conners 3-PS, WFIRS-P, CGI-I score,AEs and SAEs; S:RCTs.Condition being studied ADHD (attention deficit hyperactivity disorder) is a widespread and debilitating neuropsychiatric condition that affects children and teenagers.METHODS Participant or population Children and adolescents (6-17 years old) who were diagnosed with ADHD.Intervention Different doses of SPN-812 vs. placebo.Comparator ADHD-RS-5, Conners 3-PS, WFIRS-P, CGI-I score,AEs and SAEs.Study designs to be included Randomized controlled trials.Eligibility criteria Inclusion criteria :(1) The type of study must be an RCT; (2) language: English(3) Subjects: diagnosed ADHD patients (6-17 years old); (4) intervention: different doses of SPN-812 and placebo; (5) Indicators: ADHD-RS-5, Conners 3-PS, WFIRS-P, CGI-I score, AEs and SAEs.Case reports, case reviews, retrospective studies, and cohort studies and studies with active controls were excluded.
Institution: First Affiliated Hospital of Soochow University
Language: English
Subfield: Psychiatry and Mental health
Field: Medicine
Domain: Health Sciences
Open Access status: gold
OpenAlex ID: W4386797299