Immune response – genesis, duration, and strength in patients with moderate and severe coronavirus infection of different age groups
Year: 2023
Type: article
Study design: Observational Study
Abstract: Acquired (adaptive) immunity is a major factor determining effective immune response against a few infectious diseases. The immune response during recovery from COVID-19 is complex, involving both cellular and humoral adaptive immunity. The purpose of the study is to determine the intensity and effectiveness of the immune response at the end of the second year after discharge from the hospital in patients who have suffered from moderate and severe forms of coronavirus infection. A study among 2683 patients who suffered from moderately severe and severe coronavirus SARS-CoV2 infection with recorded complications which have not received a vaccine against SARS-nCoV-2 was performed. In the studied group of patients there were no deaths. In the whole cohort, the share of underlying prehospital comorbidity was also analyzed. The immune response induced because of moderate and severe infection with COVID-19 could serve as source of protection from recurrent severe infection for patents of different ages with various comorbidities.
Source: ZooKeys
Authors: Petar Atanasov, Maria Moneva-Sakelarieva, Yozlem Ali Kobakova, Maria Chaneva, Ivaylo Ivanov, Stefka Ivanova, Valentina Petkova
Language: English
Subfield: Infectious Diseases
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W4387075469