Work

Evaluation of Homocysteine, Trace Element, and Vitamin Levels in Male Individuals with Hemorrhoidal Disease

Year: 2023

Type: article

Abstract: Objectives: Hemorrhoidal disease is a common and uncomfortable condition affecting people worldwide, primarily in the lower rectal region. This study explores the relationship between hemorrhoidal disease and the levels of homocysteine, folic acid, vitamin B12, zinc, and copper in men. Methods: A prospective study included 38 male patients with internal hemorrhoids (Group I) and 38 healthy male individuals (Group II). Venous blood samples were collected after a 12-hour fast and analyzed for homocysteine, folic acid, vitamin B12, zinc, and copper levels. Statistical analyses, including the Kolmogorov-Smirnov test, Mann-Whitney U or Two-Sample t-test, Receiver Operating Characteristic (ROC) analysis, and Multivariate Binary Logistic regression, were performed. Results: Group I and Group II had similar age and body mass index (BMI). Homocysteine and copper levels were significantly higher in Group I, while folic acid and vitamin B12 levels were significantly lower. High homocysteine levels (≥11.2 µmol/L) had a sensitivity of 92.11%, while low vitamin B12 (

Source: MIDDLE BLACK SEA JOURNAL OF HEALTH SCIENCE

DOI: 10.19127/mbsjohs.1351713

Authors: Gürkan ÇIKIM, Solmaz SUSAM, Mustafa GÖKSU, Fatih ÜÇKARDEŞ, Muhittin ÖNDERCİ

Institution: Adıyaman University

Language: English

Topic: Anorectal Disease Treatments and Outcomes

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

Funder: Adiyaman Üniversitesi