Year: 2023
Type: article
Study design: Observational Study
Abstract: The COVID-19 pandemic is having a lasting impact on health and well-being. We compare current self-reported health, quality of life and symptom profiles for people with ongoing symptoms following COVID-19 to those who have never tested positive for SARS-CoV-2 infection and those who have recovered from COVID-19. Overall, 276,840/800,000 (34·6%) of invited participants took part. Mental health and health-related quality of life were worse among participants with ongoing persistent symptoms post-COVID compared with those who had never had COVID-19 or had recovered. In this study, median duration of COVID-related symptoms (N = 130,251) was 1·3 weeks (inter-quartile range 6 days to 2 weeks), with 7·5% and 5·2% reporting ongoing symptoms ≥12 weeks and ≥52 weeks respectively. Female sex, ≥1 comorbidity and being infected when Wild-type variant was dominant were associated with higher probability of symptoms lasting ≥12 weeks and longer recovery time in those with persistent symptoms. Although COVID-19 is usually of short duration, some adults experience persistent and burdensome illness.
Source: Nature Communications
Language: English
Subfield: Clinical Neurology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $6,290
Funders: UK Research and Innovation, National Institute for Health Research Health Protection Research Unit, National Institute for Health and Care Research, British Heart Foundation, Department of Health and Social Care, Imperial College London, UK Dementia Research Institute, MRC-PHE Centre for Environment and Health, Medical Research Council, NIHR Imperial Biomedical Research Centre, Health Data Research UK
Awards: G1210320885, Research Excellence (round 3), G1962299536, MRC-PHE Centre for Environment and Health, G2138836726, MRC Centre for Global Infectious Disease Analysis, REACT Long COVID (REACT-LC), G4132691355, Capital award for UK DRI at Imperial College London, MRC Centre for Environment and Health, NIHR Senior Investigator Award, G5208948526, G5787046253, G630072835, G6690987417, G7267735475, G869621869, G8950480773
OpenAlex ID: W4387909516