Year: 2023
Type: article
Abstract: IntroductionFor the longest time, microbiology and neuroscience used to be studied independently and with limited overlap.Recently, however, with the advancement in sequencing technology and the subsequently growing interest in metagenomics, the effect of microbial colonization on host physiology, metabolism and even behaviour has raised the question if hosts are dependent on masses of associated microorganisms [1].In 2013, after the results of the Human Microbiome Project, the United States National Institute of Mental Health launched a special research project on GMbrain axis (GMBA), in views to develop new medications or noninvasive treatments for mental diseases.Since then, studies on the influence of GM (GM) on the brain have been increasing, and the GMBA, novel mechanism used to name the bi-directional connection, has become one of the focuses on current neuroscience [2].The latest research showed that changes in GM could affect the brain's physiological, behavioral, and cognitive functions [3].Although the exact mechanism of GMBA has not yet been fully understood and clarified, the evidence from animals and human studies has showed that GM can play an important role in brain behavior Review
DOI: 10.36959/459/610
Author: Guach-Hevia David Armando
Language: English
Topic: Gut microbiota and health
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: diamond
OpenAlex ID: W4387946117