Year: 2023
Type: preprint
Study design: Observational Study
Abstract: Introduction: Meningiomas, which account for 36.4 per cent of intracranial neoplasms, predominantly affect women after the age of 50. Angiomatous meningiomas (AM), which account for 2.1% of all meningiomas, are characterised by high vascularity, which poses a challenge during surgery due to the increased risk of intraoperative haemorrhage. Objective: The aim of this study was to assess quality of life in patients with AM after surgical resection, with a focus on physical and emotional aspects. Methods: The study retrospectively analysed patients with AM who underwent surgery between 2019 and 2023 at Hospital da Restauração, Pernambuco, using the NFBrSI-24 questionnaire. Pre- and post-operative data were collected, including neurological deficits and headache intensity. Results: Of the 13 patients, 76 per cent were female, with an average age of 50.3 years. The most common preoperative symptoms included headache (30%), motor deficits (23%) and nausea/vomiting (15%). Postoperatively, improvements were seen in motor and sensory deficits, as well as a significant reduction in headache intensity. Post-operative NFBrSI-24 scores increased by an average of 15.9 points, indicating an improvement in quality of life, especially in physical and emotional aspects. Conclusions: This study is the first to investigate post-surgical quality of life in patients with AM, suggesting that surgery improves their quality of life, especially in the physical and emotional domains.
Source: Research Square
Authors: Mayle de Araújo, Pedro Negromonte, Luiz Santana, Inaê da Silva, Igor Faquini, Auricélio Junior, Hildo Filho
Institutions: Hospital da Restauração, Universidade Federal de Pernambuco
Language: English
Subfield: Clinical Neurology
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W4388127684