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High-Dose Acetaminophen with Concurrent CYP2E1 Inhibition Has Profound Anticancer Activity without Liver Toxicity

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Year: 2023
Type: article
Source: Journal of Pharmacology and Experimental Therapeutics
DOI: 10.1124/jpet.123.001772
Authors: Allyn Bryan, Pavani Pingali, Anthony Faber, Joseph Landry, Jephte Y. Akakpo, Hartmut Jaeschke, Howard Li, Won Sok Lee, Lauren May, Bhaumik Patel, Alex Neuwelt
Institutions: University of Kansas, Virginia Commonwealth University, Hunter Holmes McGuire VA Medical Center, Ralph H. Johnson VA Medical Center, University of Kansas Medical Center
Language: English

Topic: Drug-Induced Hepatotoxicity and Protection
Subfield: Pharmacology
Field: Pharmacology, Toxicology and Pharmaceutics
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: bronze

Funders: U.S. Department of Veterans Affairs, National Institutes of Health, National Institute on Aging, National Cancer Institute, National Institute of General Medical Sciences, National Center for Advancing Translational Sciences
Awards: G124318737, G1586073097, G5302702758, Massey Cancer Center - Cancer Center Support Grant, NRSA Training Core
OpenAlex ID: W4388211838
FWCI: 2.504
Cites: 41
Cited by: 11
Related to: 10
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