Year: 2023
Type: preprint
Abstract: In predictive coding (PC), higher-order brain areas generate predictions which are sent to lower-order sensory areas. Top-down predictions are compared to bottom-up sensory data, and mismatches evoke prediction error. In PC the prediction errors are encoded in layer 2/3 pyramidal neurons of sensory cortex that feed-forward. The PC model has been tested with multiple recording modalities using the global-local oddball paradigm. Consistent with PC, neuroimaging studies reported prediction error responses in sensory and higher-order areas. But recent studies of neuronal spiking suggest that genuine prediction errors emerge in prefrontal cortex. This implies that predictive processing is a more cognitive than sensory-based mechanism– an observation that challenges PC and better aligns with a framework we call predictive routing.
Authors: Kaitlyn Gabhart, Yihan Xiong, Andre Bastos
Institution: Vanderbilt University
Language: English
Subfield: Cognitive Neuroscience
Field: Neuroscience
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W4388300282