Year: 2023
Type: article
Study design: Observational Study
Abstract: Primary motor cortex alterations in Parkinson's disease (PD) are typically interpreted as a secondary consequence of nigrostriatal dopaminergic degeneration and altered basal ganglia output. In a relatively large cross-sectional study, we recently observed that cortical disinhibition in PD appears to be independent on the stage of the disease, as measured through short-interval intracortical inhibition (SICI) using transcranial magnetic stimulation (TMS). This finding suggests that cortical disinhibition may not be related to the level of nigrostriatal degeneration and altered basal ganglia output throughout the evolution disease after diagnosis (i.e.
Source: IBRO Neuroscience Reports
Authors: Claudia Ammann, Michele Dileone, Cristina Pagge, David Mata-Marín, Michele Matarrazzo, Mariana H.G. Monje, Álvaro Sánchez-Ferro, Beatriz Fernández-Rodríguez, Carmen Gasca-Salas, Jorge Máñez-Miró, Raúl Martínez-Fernández, Lydia Vela-Desojo, Fernando Alonso-Frech, Antonio Oliviero, Jose Ángel Obeso, Guglielmo Foffani
Language: English
Subfield: Neurology
Field: Neuroscience
Domain: Life Sciences
Open Access status: gold
Estimated APC paid: $1,500
OpenAlex ID: W4388364122